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Cancer =96 Press Review  =96 Revue de Presse

Every week on http://marclacroixcancerblog.blogspot.com
Chaque semaine sur http://marclacroixcancerblog.blogspot.com


Press Review (December 29, 2012) =96 Revue de presse (29 d=E9cembre 2012)

Elwood V. Jensen, Pioneer in Breast Cancer Treatment, Dies at 92
Elwood V. Jensen, a medical researcher whose studies of steroid
hormones led to new treatments for breast cancer that have been
credited with saving or extending hundreds of thousands of lives, died
on Dec. 16 in Cincinnati. He was 92.
By Daniel E. Slotnik. In The New York Times
http://www.nytimes.com/2012/12/27/us/elwood-v-jensen-pioneer-in-breast-canc=
er-treatment-dies-at-92.html?_r=3D0

US cancer screening rates decline over the last 10 years, finds new
study
The rate of people who seek preventive cancer screenings has fallen
over the last ten years in the United States with wide variations
between white-collar and blue-collar workers, according to a
University of Miami Miller School of Medicine study published on
December 27 in the open-access journal Frontiers in Cancer
Epidemiology.
In EurekAlert (press release)
http://www.eurekalert.org/pub_releases/2012-12/f-ucs122112.php

Anti-Androgen Therapies to Prevent Prostate Cancer Are Not One Size
Fits All
A new study suggests that chemoprevention with anti-androgen therapies
may not benefit all patients at risk for prostate cancer and could
cause harm to some. Researchers at the Dana-Farber Cancer Institute
and Harvard Medical School have identified a genetic mutation that
actually results in a more robust transition from a precancerous to
cancerous state when exposed to androgen deprivation.
By Anna Azvolinsky. In Cancer Network
http://www.cancernetwork.com/prostate-cancer/content/article/10165/2120872

Ability to Metabolize Tamoxifen Affects Breast Cancer Outcomes
For nearly a decade, breast cancer researchers studying the hormone
therapy tamoxifen have been divided as to whether genetic differences
in a liver enzyme affect the drug's effectiveness and the likelihood
breast cancer will recur. A new study by researchers from the Mayo
Clinic Cancer Center and the Austrian Breast and Colorectal Cancer
Study Group provides evidence that genetic differences in the enzyme
CYP2D6 play a key role in how well tamoxifen work.
In Science Daily (press release)
http://www.sciencedaily.com/releases/2012/12/121226153030.htm

Breast cancer cells interact with non-cancerous tissue to drive
metastasis
In addition to mutations, environmental conditions created by the
tissues surrounding tumors (stroma) play a major role in cancer
progression. Researchers led by Gregg Semenza at Johns Hopkins
University examined the interactions between breast cancer cells and
the stroma to identify underlying pro-metastatic molecular mechanisms.
In Science Codex
http://www.sciencecodex.com/breast_cancer_cells_interact_with_noncancerous_=
tissue_to_drive_metastasis-104411

NIH study suggests gene variation may shape bladder cancer treatment
Patients who have inherited a specific common genetic variant develop
bladder cancer tumors that strongly express a protein known as
prostate stem cell antigen (PSCA), which is also expressed in many
pancreatic and prostate tumors, according to research at the National
Institutes of Health.
In National Institutes of Health (press release)
http://www.nih.gov/news/health/dec2012/nci-26.htm

Cyclin D1b is a genetic reprogrammer that drives cancer progression
Researchers led by Karen Knudsen at Thomas Jefferson University's
Kimmel Cancer Center examined the role of cyclin D1b in prostate
cancer.
In Science Codex
http://www.sciencecodex.com/cyclin_d1b_is_a_genetic_reprogrammer_that_drive=
s_cancer_progression-104408

Bowel cancer gene discovery cracks mystery of families with a strong
history of the disease
Cancer Research UK-funded scientists have discovered that two gene
faults increase the risk of bowel cancer in families with a strong
history of developing the disease, who, until now, had no explanation
as to why their risk was greater. The research is published in Nature
Genetics.
In Cancer Research UK
http://www.cancerresearchuk.org/cancer-info/news/archive/pressrelease/2012-=
12-23-bowel-cancer-gene-find?view=3Drss

What Is a Meaningful Increased Survival?
In their quest for new agents, pharmaceutical researchers test
millions of substances all over the world. They like using color-
forming reactions to identify new molecules. However, in intensively
colored solutions or in the case of mixtures with multiple substances
these tests fail. As part of his doctoral thesis, Martin Stein, member
of staff at the Chair of Biochemistry at the Technische Universitaet
Muenchen, developed a testing reaction based on magnetic resonance
data. It helps find a specific pharmaceutical molecule among hundreds
of different substances even in the most turbid of bacterial brews
By Rebecca Bechhold. In Cancer Network (blog)
http://www.cancernetwork.com/blog/content/article/10165/2120849


D=E9couverte de deux g=EAnes responsables du cancer de l'intestin
Des chercheurs britanniques pensent avoir trouv=E9 pourquoi certaines
familles sont tr=E8s expos=E9es au cancer de l=92intestin. Deux g=EAnes,
transmis par les parents aux enfants, seraient en effet responsables
de l=92augmentation du risque de formation d'une tumeur.
Dans JOL Press
http://www.jolpress.com/sante-cancer-intestin-colorectal-genes-antecedants-=
familiaux-article-815999.html

Cancer de la prostate: Un virus cach=E9 dans un macrophage pour tuer la
tumeur
C=92est =E0 nouveau l=92approche par virus oncolytique, un virus capable
d=92infecter uniquement les cellules canc=E9reuses et de les d=E9truire, qu=
i
vient d=92=EAtre test=E9e pour le traitement du cancer avanc=E9 de la prost=
ate
chez l'homme.
Dans Sant=E9.log
http://www.santelog.com/news/cancerologie/cancer-de-la-prostate-un-virus-ca=
che-dans-un-macrophage-tue-la-tumeur-chez-la-souris_9603.htm

Le d=E9pistage du cancer du col de l'ut=E9rus gratuit d=E8s le 1er janvier
Le d=E9pistage du cancer du col de l'ut=E9rus sera gratuit dans quelques
jours. Les frottis (qui co=FBtent aujourd'hui 13 euros aux patientes)
seront int=E9gralement rembours=E9s. C'est l'une des d=E9cisions prises
vendredi soir lors du dernier Conseil des ministres de l'ann=E9e.
Sur RTBF
http://www.rtbf.be/info/societe/detail_le-depistage-du-cancer-du-col-de-l-u=
terus-gratuit-des-le-1er-janvier?id=3D7897282

La cigarette affecterait les g=E8nes du cancer
Le fait de fumer des cigarettes pourrait affecter les g=E8nes du cancer
dans l=92ADN, montrant que la consommation de tabac alt=E8rerait
chimiquement l=92activit=E9 des g=E8nes faisant augmenter le risque de
cancer.
Par Sandra Besson. Dans Actualit=E9s News Environnement
http://www.actualites-news-environnement.com/29803-cigarette-gene-cancer.ht=
ml

Cancer du sein en Alg=E9rie : 3 000 d=E9c=E8s d'Alg=E9riennes par an
Environ 9 000 nouveaux cas de cancer du sein sont d=E9couverts chaque
ann=E9e en Alg=E9rie, et plus de 3000 victimes en meurent.
Par J Boukraa. Dans Mondeactu.com
http://mondeactu.com/2012/12/24/cancer-du-sein-en-algerie-3-000-deces-dalge=
riennes-par-an-12440


Cancer Blog =96 Marc Lacroix =96 Le Blogue du Cancer
http://marclacroixcancerblog.blogspot.com


Marc Lacroix-Corman =96 InTextoResearch =96 Baelen  (12/2012)